Title : Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid.

Pub. Date : 2016 Jun 24

PMID : 27129261






1 Functional Relationships(s)
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1 We show by using lipidomics that thrombin-activated human platelets generate a new type of eicosanoid that both stimulates and primes human neutrophil integrin (Mac-1) expression, in response to formylmethionylleucylphenylalanine. N-Formylmethionine Leucyl-Phenylalanine coagulation factor II, thrombin Homo sapiens