Title : Copper-Catalyzed Cascade Reaction via Intramolecular Hydroamination Cyclization of Homopropargylic Amines and Intermolecular Povarov Reaction with Imines.

Pub. Date : 2016 May 20

PMID : 27128977






1 Functional Relationships(s)
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1 A new one-pot cascade reaction of homopropargylic amines with simple imines is developed in the presence of Cu(OTf)2 and affords a series of hexahydro-1H-pyrrolo[3,2-c]quinoline derivatives in good to high yields. Amines POU class 2 homeobox 2 Homo sapiens