Pub. Date : 2016 Apr 26
PMID : 27128949
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tacrolimus Modulates TGF-beta Signaling to Induce Epithelial-Mesenchymal Transition in Human Renal Proximal Tubule Epithelial Cells. | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |
| 2 | FK506 effects on TGF-beta mRNA were assessed by RT PCR and TGF-beta secretion was measured by ELISA. | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |
| 3 | Additionally, the study demonstrates that FK506 activation of the TGF-beta/ SMAD pathways is an essential step in the EMT process. | Tacrolimus | transforming growth factor beta 1 | Homo sapiens |