Title : Mouse liver P450Coh: genetic regulation of the pyrazole-inducible enzyme and comparison with other P450 isoenzymes.

Pub. Date : 1989 May 15

PMID : 2712571






3 Functional Relationships(s)
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1 The inducibility of coumarin 7-hydroxylase by phenobarbital (PB) and its genetic regulation have been previously studied by A. W. Wood and colleagues ((1974) Science 185, 612-614; (1979); J. Biol. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
2 The inducibility of coumarin 7-hydroxylase by phenobarbital (PB) and its genetic regulation have been previously studied by A. W. Wood and colleagues ((1974) Science 185, 612-614; (1979); J. Biol. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus
3 Immunoinhibition of microsomal coumarin 7-hydroxylase is practically 100% for control animals and after pretreatment with pyrazole or PB. Phenobarbital cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus