Title : Investigation of the Sequential Actions of Doxorubicin and p53 on Tumor Cell Growth Via Branched Polyethylenimine-β-cyclodextrin Conjugates.

Pub. Date : 2016 Nov

PMID : 27122200






2 Functional Relationships(s)
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1 Investigation of the Sequential Actions of Doxorubicin and p53 on Tumor Cell Growth Via Branched Polyethylenimine-beta-cyclodextrin Conjugates. Polyethyleneimine tumor protein p53 Homo sapiens
2 Briefly, branched polyethylenimine (BPEI) was conjugated with beta-cyclodextrin hydrate (beta-CD) to form BPEI-beta-CD backbone, and p53 plasmid was condensed by positively charged BPEI via electrostatic interaction, while Dox was first conjugated with adamantine (AD) and then assembled with BPEI-beta-CD backbone via the host-guest interaction. Polyethyleneimine tumor protein p53 Homo sapiens