Pub. Date : 2016 Jun
PMID : 27121011
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin ameliorates ventricular remodeling via the TGF-beta1 signaling pathway in rats following myocardial infarction. | Simvastatin | transforming growth factor, beta 1 | Rattus norvegicus |
| 2 | The results revealed that simvastatin significantly improved the hemodynamic indexes, left ventricular mass index, the myocardial tissue structure, the cardiomyocyte cross-sectional area and the collagen volume fraction, and also showed that the levels of TGF-beta1, TGF-activated kinase (TAK)1 and drosophila mothers against decapentaplegic (Smad)3 were significantly reduced following treatment with simvastatin, while the levels of Smad7 in the simvastatin treatment groups were markedly increased. | Simvastatin | transforming growth factor, beta 1 | Rattus norvegicus |