Title : Nuclear factor erythroid-derived 2-like 2 (NFE2L2, Nrf2) mediates exercise-induced mitochondrial biogenesis and the anti-oxidant response in mice.

Pub. Date : 2016 Sep 15

PMID : 27094017






1 Functional Relationships(s)
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1 In C2C12 myoblasts, acute treatment with exogenous H2 O2 (ROS)- and diethylenetriamine/NO adduct (NO donor) induced increases in mtTFA, which was prevented by small interfering RNA and short hairpin RNA knockdown of either NFE2L2 or NRF-1. diethylenetriamine transcription factor A, mitochondrial Homo sapiens