Title : Discovery and analgesic evaluation of 8-chloro-1,4-dihydropyrido[2,3-b]pyrazine-2,3-dione as a novel potent d-amino acid oxidase inhibitor.

Pub. Date : 2016 Jul 19

PMID : 27089209






1 Functional Relationships(s)
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1 This research not only confirmed the analgesic effect of the DAAO inhibitors but provided a new class of chemical entities with oral application potential for the treatment of chronic pain and morphine analgesic tolerance. Morphine D-amino acid oxidase Homo sapiens