Title : Bacillus-produced surfactin attenuates chronic inflammation in atherosclerotic lesions of ApoE(-/-) mice.

Pub. Date : 2016 Jun

PMID : 27082998






2 Functional Relationships(s)
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1 Further investigation discovered that surfactin also systemically induced CD4(+)CD25(+)FoxP3(+) Tregs in spleen, which could inhibit T cells to produce pro-inflammatory cytokines such as tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma. surfactin peptide tumor necrosis factor Mus musculus
2 As a result, the attenuation of chronic inflammation was observed in the surfactin-treated groups accompanying with less TNF-alpha but more IL-10 in the atherosclerotic lesions. surfactin peptide tumor necrosis factor Mus musculus