Title : Curcumin and epithelial-mesenchymal transition in breast cancer cells transformed by low doses of radiation and estrogen.

Pub. Date : 2016 Jun

PMID : 27082017






1 Functional Relationships(s)
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1 Results indicated that curcumin decreased expression of EMT-related genes in Tumor2 cell line when compared to its counterpart as E-cadherin, N-cadherin, ZEB2, Twist1, Slug, Axl, vimentin, STAT-3, fibronectin; and genes p53 and caveolin-1, as well as apoptotic genes caspase-3, caspase-8, and others such as cyclin D1 and NFkappaB. Curcumin caspase 8 Homo sapiens