Title : Regulation of growth hormone gene expression: synergistic effects of thyroid and glucocorticoid hormones.

Pub. Date : 1977 Oct

PMID : 270674






2 Functional Relationships(s)
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1 In cells maintained for 5 days in hypothyroid medium, triiodothyronine induces within 50 hr a 17-fold increase in growth hormone production whereas glucocorticoids, during the same time, produce a negligible (3-fold or less) stimulation. Triiodothyronine gonadotropin releasing hormone receptor Rattus norvegicus
2 The results also show that triiodothyronine controls the magnitude of the effect of glucocorticoids on growth hormone mRNA, and provide a model for "permissive" triiodothyronine action. Triiodothyronine gonadotropin releasing hormone receptor Rattus norvegicus