Title : Icariside II, a natural mTOR inhibitor, disrupts aberrant energy homeostasis via suppressing mTORC1-4E-BP1 axis in sarcoma cells.

Pub. Date : 2016 May 10

PMID : 27056897






1 Functional Relationships(s)
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1 Furthermore, IS inhibits the cap-dependent translation of c-myc through mTORC1-4E-BP1 axis which links the relationship between mRNA translation and glycolysis. cap MYC proto-oncogene, bHLH transcription factor Homo sapiens