Pub. Date : 2016 Apr
PMID : 27055524
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A mechanism-based 3D-QSAR approach for classification and prediction of acetylcholinesterase inhibitory potency of organophosphate and carbamate analogs. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Organophosphate (OP) and carbamate esters can inhibit acetylcholinesterase (AChE) by binding covalently to a serine residue in the enzyme active site, and their inhibitory potency depends largely on affinity for the enzyme and the reactivity of the ester. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | Organophosphate (OP) and carbamate esters can inhibit acetylcholinesterase (AChE) by binding covalently to a serine residue in the enzyme active site, and their inhibitory potency depends largely on affinity for the enzyme and the reactivity of the ester. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |