Pub. Date : 2016 Jun
PMID : 27035545
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Diallyl trisulfide induces osteosarcoma cell apoptosis through reactive oxygen species-mediated downregulation of the PI3K/Akt pathway. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | DATS induced apoptosis in the MG63 and MNNG/HOS cells via inhibition of the PI3K/Akt signaling pathway and through the mitochondrial apoptotic pathway. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | However, N-acetylcysteine (NAC), a general ROS scavenger, completely blocked the DATS-induced ROS increase, inhibition of the PI3K/Akt pathway and cell apoptosis. | diallyl trisulfide | AKT serine/threonine kinase 1 | Homo sapiens |