Title : Genetic and epigenetic factors affect RET gene expression in breast cancer cell lines and influence survival in patients.

Pub. Date : 2016 May 3

PMID : 27034161






2 Functional Relationships(s)
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1 More recently, RET over-expression has emerged as a new player in ER-positive (ER+) BC, and as a potential target to enhance sensitivity and avoid resistance to tamoxifen therapy.Therefore, targeting the RET pathway may lead to new therapies in ER+ BC. Tamoxifen ret proto-oncogene Homo sapiens
2 More recently, RET over-expression has emerged as a new player in ER-positive (ER+) BC, and as a potential target to enhance sensitivity and avoid resistance to tamoxifen therapy.Therefore, targeting the RET pathway may lead to new therapies in ER+ BC. Tamoxifen ret proto-oncogene Homo sapiens