Title : Evidence that the adenosine triphosphate-binding cassette G5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice.

Pub. Date : 2016 Sep

PMID : 27014967






1 Functional Relationships(s)
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1 Although ABCG5/G8 plays a critical role in determining hepatic sterol secretion, cholesterol is still secreted to bile in sitosterolemic patients with a defect in either ABCG5 or ABCG8 and in either Abcg5/g8 double- or single-knockout mice. Cholesterol ATP binding cassette subfamily G member 5 Homo sapiens