Pub. Date : 2016 Jun 2
PMID : 27006390
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this article, we show that, instead of disturbed heparin interactions, the impaired ability of C-terminal mutant FH molecules to recognize sialic acid in the context of surface-bound C3b explains their pathogenicity. | N-Acetylneuraminic Acid | complement C3 | Homo sapiens |
2 | Proper formation of FH-sialic acid-C3b complexes on surfaces exposed to plasma is essential for preventing cell damage and thrombogenesis characteristic of aHUS. | N-Acetylneuraminic Acid | complement C3 | Homo sapiens |