Pub. Date : 2016 Apr 19
PMID : 27003727
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For IDI-2 from the pathogenic bacterium Streptococcus pneumoniae, the flavin can be treated kinetically as a dissociable cosubstrate in incubations with IPP and excess NADH. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |
| 2 | Dithionite reduction of FMN in the IDI-2 FMN and IPP mixture was biphasic with k(red)(IDI-2 FMN IPP (fast)) = 326 s(-1) and k(red)(IDI-2 FMN IPP (slow)) = 6.9 s(-1) The pseudo-first-order rate constant for the slow component was similar to those for NADH reduction of the flavin in the IDI-2 FMN and IPP mixture and may reflect a rate-limiting conformational change in the enzyme. | 4,6-dinitro-o-cresol | isopentenyl-diphosphate delta isomerase 2 | Homo sapiens |