Title : Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage.

Pub. Date : 2016 Jun

PMID : 27003683






1 Functional Relationships(s)
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1 METHODS: We created whole-body tamoxifen-inducible leptin receptor (LepR)-deficient mice (Ubc-Cre (ERT2) LepR (loxP/loxP) ) as a novel model of acute obesity. Tamoxifen mitogen-activated protein kinase 3 Mus musculus