Title : Nonsense-mediated decay regulates key components of homologous recombination.

Pub. Date : 2016 Jun 20

PMID : 27001511






1 Functional Relationships(s)
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1 Regulation of HR by NMD extends to multiple targets beyond RAD55, including RAD51, RAD54 and RAD57 Finally, we demonstrate that loss of NMD results in an increase in recombination rates and resistance to the DNA damaging agent methyl methanesulfonate, suggesting this pathway negatively regulates HR under normal growth conditions. Methyl Methanesulfonate DNA-dependent ATPase RAD54 Saccharomyces cerevisiae S288C