Title : Selective Tuberous Sclerosis Complex 1 Gene Deletion in Smooth Muscle Activates Mammalian Target of Rapamycin Signaling and Induces Pulmonary Hypertension.

Pub. Date : 2016 Sep

PMID : 26991739






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with 5 mg/kg rapamycin for 3 weeks to inhibit mTORC1 and mTORC2 fully reversed PH in SM22-TSC1(-/-) mice. Sirolimus TSC complex subunit 1 Mus musculus