Title : Gastrodin suppresses BACE1 expression under oxidative stress condition via inhibition of the PKR/eIF2α pathway in Alzheimer's disease.

Pub. Date : 2016 Jun 14

PMID : 26987953






1 Functional Relationships(s)
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1 Moreover, peptide PKR inhibitor (PRI) and Gas down-regulated BACE1 expression in Tg2576 mice and H2O2-stimulated SH-SY5Y cells by inhibiting activation of PKR and eIF2alpha. Hydrogen Peroxide eukaryotic translation initiation factor 2A Homo sapiens