Pub. Date : 2016 May 15
PMID : 26976925
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human DC-SIGN binds specific human milk glycans. | Polysaccharides | CD209 molecule | Homo sapiens |
| 2 | Unexpectedly, DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) showed robust binding to many HMGs, whereas other C-type lectins failed to bind, and Siglec-5 and Siglec-9 showed weak binding to a few glycans. | Polysaccharides | CD209 molecule | Homo sapiens |
| 3 | Unexpectedly, DC-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) showed robust binding to many HMGs, whereas other C-type lectins failed to bind, and Siglec-5 and Siglec-9 showed weak binding to a few glycans. | Polysaccharides | CD209 molecule | Homo sapiens |
| 4 | Binding of DC-SIGN to the simple HMGs 2"-fucosyl-lactose (2"-FL) and 3-fucosyl-lactose (3-FL) was confirmed by flow cytometry to beads conjugated with 2"-FL or 3-FL, as well as the ability of the free glycans to inhibit DC-SIGN binding. | Polysaccharides | CD209 molecule | Homo sapiens |