Title : The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A.

Pub. Date : 2016 Mar 22

PMID : 26972007






1 Functional Relationships(s)
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1 In normoxia, PHD2 hydroxylates the proline residues P2309 and P2316 in FLNA, leading to von Hippel-Lindau (VHL)-mediated ubiquitination and proteasomal degradation. Proline von Hippel-Lindau tumor suppressor Homo sapiens