Title : [Ranitidine protects the human stomach and duodenal mucosa against low-dose acetylsalicylic acid].

Pub. Date : 1989 Dec

PMID : 2697116






3 Functional Relationships(s)
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1 In a randomized double-blind study the gastroduodenal tolerability of 300 mg ASS daily has been evaluated in the presence of 150 mg ranitidine bid or placebo in 20 healthy volunteers using upper GI-endoscopy. Ranitidine BH3 interacting domain death agonist Homo sapiens
2 Concomitant administration of 150 mg ranitidine bid afforded almost full protection against 300 mg ASS daily both on day 7 and day 14 (1.9 +/- 0.6 and 2.1 +/- 0.8, respectively) (p less than 0.05). Ranitidine BH3 interacting domain death agonist Homo sapiens
3 Our data suggest that coadministration of ranitidine 150 mg bid reduces almost completely gastroduodenal lesions evoked by acetylsalicylic acid 300 mg daily. Ranitidine BH3 interacting domain death agonist Homo sapiens