Title : Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells.

Pub. Date : 2016 Apr 15

PMID : 26966071






1 Functional Relationships(s)
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1 Treatment with dexamethasone, phenobarbital, rifampicin, or 1alpha,25-dihydroxyvitamin D3 resulted in 5.8-fold, 13.4-fold, 9.8-fold, or 95.0-fold induction of CYP3A4 expression relative to that in the untreated controls, respectively. Phenobarbital cytochrome P450 family 3 subfamily A member 4 Homo sapiens