Title : 20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition.

Pub. Date : 2016 May 1

PMID : 26921441






1 Functional Relationships(s)
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1 20-Hydroxyeicosatetraeonic acid (20-HETE) produced by cytochrome P-450 monooxygenases in NADPH-dependent manner is proinflammatory, and it contributes to the pathogenesis of systemic and pulmonary hypertension. NADP cytochrome P450 family 4 subfamily F member 3 Homo sapiens