Title : IFN-α promotes rapid human Treg contraction and late Th1-like Treg decrease.

Pub. Date : 2016 Sep

PMID : 26921346






2 Functional Relationships(s)
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1 First, IFN-alpha exerts a rapid, antiproliferative and proapoptotic effect in vitro and in vivo, as early as after 2 d of pegylated IFN/ribavirin therapy in patients with chronic hepatitis C. Such activities result in the decline, at d 2, in circulating regulatory T cell frequency and specifically of the activated regulatory T cell subset. Ribavirin interferon alpha 1 Homo sapiens
2 First, IFN-alpha exerts a rapid, antiproliferative and proapoptotic effect in vitro and in vivo, as early as after 2 d of pegylated IFN/ribavirin therapy in patients with chronic hepatitis C. Such activities result in the decline, at d 2, in circulating regulatory T cell frequency and specifically of the activated regulatory T cell subset. Ribavirin interferon alpha 1 Homo sapiens