Title : Clinical determinants of calcineurin inhibitor disposition: a mechanistic review.

Pub. Date : 2016

PMID : 26912097






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclosporine disposition is less susceptible to these interactions compared with tacrolimus, possibly because cyclosporine is itself a moderately strong CYP3A4- and strong P-gp inhibitor, blunting the effect of additional inhibitors. Cyclosporine ATP binding cassette subfamily B member 1 Homo sapiens
2 Cyclosporine disposition is less susceptible to these interactions compared with tacrolimus, possibly because cyclosporine is itself a moderately strong CYP3A4- and strong P-gp inhibitor, blunting the effect of additional inhibitors. Cyclosporine ATP binding cassette subfamily B member 1 Homo sapiens