Title : Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice.

Pub. Date : 2016 Aug

PMID : 26909542






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Mice lacking the endogenous beta2-adrenoceptor (beta2AR) agonist epinephrine (phenylethanolamine N-methyltransferase [PNMT]-knockout mice) are resistant to developing an "asthma-like" phenotype in an ovalbumin sensitization and challenge (Ova S/C) model, and chronic administration of beta2AR agonists to PNMT-KO mice restores the phenotype. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
2 Mice lacking the endogenous beta2-adrenoceptor (beta2AR) agonist epinephrine (phenylethanolamine N-methyltransferase [PNMT]-knockout mice) are resistant to developing an "asthma-like" phenotype in an ovalbumin sensitization and challenge (Ova S/C) model, and chronic administration of beta2AR agonists to PNMT-KO mice restores the phenotype. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus
3 Mice lacking the endogenous beta2-adrenoceptor (beta2AR) agonist epinephrine (phenylethanolamine N-methyltransferase [PNMT]-knockout mice) are resistant to developing an "asthma-like" phenotype in an ovalbumin sensitization and challenge (Ova S/C) model, and chronic administration of beta2AR agonists to PNMT-KO mice restores the phenotype. Epinephrine phenylethanolamine-N-methyltransferase Mus musculus