Title : Variability in Capsaicin-stimulated Calcitonin Gene-related Peptide Release from Human Dental Pulp.

Pub. Date : 2016 Apr

PMID : 26898566






7 Functional Relationships(s)
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1 Variability in Capsaicin-stimulated Calcitonin Gene-related Peptide Release from Human Dental Pulp. Capsaicin calcitonin related polypeptide alpha Homo sapiens
2 Tooth slices from 36 patients were exposed to 60 mumol/L capsaicin to stimulate the release of calcitonin gene-related peptide (CGRP) from nerve terminals in the pulp. Capsaicin calcitonin related polypeptide alpha Homo sapiens
3 Tooth slices from 36 patients were exposed to 60 mumol/L capsaicin to stimulate the release of calcitonin gene-related peptide (CGRP) from nerve terminals in the pulp. Capsaicin calcitonin related polypeptide alpha Homo sapiens
4 Patient factors were analyzed for their effects on capsaicin-stimulated CGRP release using a mixed model analysis of variance. Capsaicin calcitonin related polypeptide alpha Homo sapiens
5 RESULTS: Approximately one third of the variability observed in capsaicin-evoked CGRP release was attributable to differences between individuals. Capsaicin calcitonin related polypeptide alpha Homo sapiens
6 Using a within-subject study design, a significant effect of capsaicin on CGRP release was observed. Capsaicin calcitonin related polypeptide alpha Homo sapiens
7 CONCLUSIONS: Capsaicin-stimulated CGRP release from dental pulp is highly variable between individuals. Capsaicin calcitonin related polypeptide alpha Homo sapiens