Title : Combination of metformin and 5-aminosalicylic acid cooperates to decrease proliferation and induce apoptosis in colorectal cancer cell lines.

Pub. Date : 2016 Feb 19

PMID : 26896068






1 Functional Relationships(s)
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1 Moreover, metformin enhanced the anti-inflammatory effect of 5-ASA by decreasing the gene expression of IL-1beta, IL-6, COX-2 and TNF-alpha and its receptors; TNF-R1 and TNF-R2. Metformin mitochondrially encoded cytochrome c oxidase II Homo sapiens