Title : Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.

Pub. Date : 2016 Apr 15

PMID : 26887940






1 Functional Relationships(s)
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1 We showed that activity and processivity of hTERT-T726M failed to be stimulated by TPP1-POT1 overexpression and that dGTP usage by this variant was less efficient compared with the wild-type enzyme. deoxyguanosine triphosphate telomerase reverse transcriptase Homo sapiens