Title : Metformin inhibits salivary adenocarcinoma growth through cell cycle arrest and apoptosis.

Pub. Date : 2015

PMID : 26885449






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In association with the reduction of MYC onco-protein, metformin significantly restored p53 tumor suppressor gene expression. Metformin tumor protein p53 Homo sapiens
2 The distinctive effects of metformin and PP242 on MYC reduction and P53 restoration suggested that metformin inhibited cell growth through a different pathway from PP242 in salivary carcinoma cells. Metformin tumor protein p53 Homo sapiens