Title : Constructing aptamer anchored nanovesicles for enhanced tumor penetration and cellular uptake of water soluble chemotherapeutics.

Pub. Date : 2016 Apr 15

PMID : 26873366






1 Functional Relationships(s)
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1 In this research, by taking advantage of the supermolecular interactions between amphiphilic graft polyphosphazene and cholesterol which was linked to aptamer AS1411, we prepared a targeted functional polymersome (PEP-DOX HCl-Ap) through a simple method with high loading of water soluble anti-cancer drug doxorubicin hydrochloride. Cholesterol prolyl endopeptidase Mus musculus