Title : Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects.

Pub. Date : 2016 Jul

PMID : 26852904






1 Functional Relationships(s)
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1 The FFA2 receptor (known as GPR43) is activated by short chain fatty acids (SCFA) such as acetate and has been shown to play a major role in SCFA-induced neutrophil activation and migration and to contribute in the development and control of inflammation. Fatty Acids, Volatile free fatty acid receptor 2 Homo sapiens