Pub. Date : 2016 May
PMID : 26852666
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Addition of GAM to Muller cell culture repressed insulin-induced activation of the Akt/mTORC1 signaling pathway. | Glucosamine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Instead, GAM induced ER stress and subsequent expression of the protein Regulated in DNA Damage and Development (REDD1), which was necessary for GAM to repress insulin-stimulated phosphorylation of Akt on Thr308. | Glucosamine | AKT serine/threonine kinase 1 | Homo sapiens |