Pub. Date : 2016 Mar
PMID : 26848042
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | IFN-beta knockdown decreased the poly (I:C)-induced production of ROS and DNA damage, restored Psim and cytochrome c release, and suppressed caspase-9 and -3 activation, thereby suppressing poly (I:C)-mediated apoptosis in the HeLa cells. | Reactive Oxygen Species | interferon beta 1 | Homo sapiens |
| 2 | Together, the results of the present study demonstrated that poly (I:C) transfection induced IFN-beta, contributing to ROS production, DNA damage, and caspase-9 and -3 activation in the HeLa cervical cancer cell line, leading to mitochondrial-mediated apoptosis. | Reactive Oxygen Species | interferon beta 1 | Homo sapiens |