Pub. Date : 2016 May
PMID : 26836250
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High levels of L-leucine and glucose lead to higher phosphorylation of mTORC1 and its downstream target ribosomal S6 kinase 1 (S6K1) in these embryos. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |
| 2 | Further, L-leucine supplementation resulted in higher embryonic expression of genes involved in cell cycle (cyclin D1; CCND1), translation initiation (eukaryotic translation initiation factor 4E; EIF4E), amino acid transport (large neutral amino acid transporter 2; Lat2: gene SLC7A8) and proliferation (proliferating cell nuclear antigen; PCNA) in a mTORC1-dependent manner. | Leucine | CREB regulated transcription coactivator 1 | Mus musculus |