Pub. Date : 2016 May 20
PMID : 26801633
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-kappaB Activation. | diallyl trisulfide | metallothionein 2A | Homo sapiens |
| 2 | The present study investigated the effect of diallyl trisulfide (DATS), a garlic-derived compound, and docetaxel (DOC) on regulation of MT2A in relation to NF-kappaB in GC cells. | diallyl trisulfide | metallothionein 2A | Homo sapiens |
| 3 | The present study investigated the effect of diallyl trisulfide (DATS), a garlic-derived compound, and docetaxel (DOC) on regulation of MT2A in relation to NF-kappaB in GC cells. | diallyl trisulfide | metallothionein 2A | Homo sapiens |
| 4 | The anti-GC effect of DATS was attributable to its capacity to epigenetically upregulate MT2A, which in turn enhanced transcription of IkappaB-alpha to suppress NF-kappaB activation in GC cells. | diallyl trisulfide | metallothionein 2A | Homo sapiens |
| 5 | INNOVATION AND CONCLUSION: We conclude that DATS exerts its anti-GC activity and enhances chemosensitivity of GC to DOC by epigenetic upregulation of MT2A to attenuate NF-kappaB signaling. | diallyl trisulfide | metallothionein 2A | Homo sapiens |