Title : Intrinsic thermodynamics of inhibitor binding to human carbonic anhydrase IX.

Pub. Date : 2016 Apr

PMID : 26794023






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Various synthetic aromatic sulfonamide-bearing compounds are being designed as potent inhibitors of CA IX. Sulfonamides carbonic anhydrase 9 Homo sapiens
2 However, sulfonamide compound binding to CA IX is linked to several reactions, the deprotonation of the sulfonamide amino group and the protonation of the CA active site Zn(II)-bound hydroxide. Sulfonamides carbonic anhydrase 9 Homo sapiens
3 However, sulfonamide compound binding to CA IX is linked to several reactions, the deprotonation of the sulfonamide amino group and the protonation of the CA active site Zn(II)-bound hydroxide. Sulfonamides carbonic anhydrase 9 Homo sapiens