Pub. Date : 2016 Apr 1
PMID : 26791486
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Iodide excess regulates its own efflux: a possible involvement of pendrin. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |
| 2 | Previous studies demonstrated that pendrin is able to mediate apical efflux of iodide in thyrocytes. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |
| 3 | Our results indicate that iodide excess increases pendrin abundance and plasma membrane insertion after 24 h of treatment. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |
| 4 | Moreover, iodide excess increases pendrin half-life. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |
| 5 | In conclusion, these data suggest that pendrin may have an important role in mediating iodide efflux in thyrocytes, especially under conditions of iodide excess. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |
| 6 | In conclusion, these data suggest that pendrin may have an important role in mediating iodide efflux in thyrocytes, especially under conditions of iodide excess. | Iodides | solute carrier family 26 member 4 | Rattus norvegicus |