Title : Thymosin Beta-4 Suppresses Osteoclastic Differentiation and Inflammatory Responses in Human Periodontal Ligament Cells.

Pub. Date : 2016

PMID : 26789270






1 Functional Relationships(s)
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1 Tbeta4 activation with a Tbeta4 peptide attenuated the H2O2-induced production of NO and PGE2 and up-regulated iNOS, COX-2, and osteoclastogenic cytokines (TNF-alpha, IL-1beta, IL-6, IL-8, and IL-17) as well as reversed the effect on RANKL and OPG in PDLCs. Hydrogen Peroxide interleukin 1 beta Homo sapiens