Pub. Date : 2016 Apr
PMID : 26780347
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The oxidative stresses also modulate kinase activity of RET-PTC1 with cysteine 365 (C365) replaced by alanine with promotion of dimer formation, but not with cysteine 376 (C376) replaced by alanine. | Cysteine | ret proto-oncogene | Homo sapiens |
| 2 | Since C376 of Ret-PTC-1 or its equivalent is most highly conserved and crucial for activity in PTKs, the cysteine could be one of major targets for oxidative stresses. | Cysteine | ret proto-oncogene | Homo sapiens |