Title : The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4.

Pub. Date : 2016 May

PMID : 26774838






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4. Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 In order to better understand structural and functional aspects of binding of multiple substrate molecules to CYP3A4 we used resonance Raman and UV-VIS spectroscopy to document the effects of binding of synthetic testosterone dimers of different configurations, cis-TST2 and trans-TST2. Testosterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens