Title : p53 coordinates base excision repair to prevent genomic instability.

Pub. Date : 2016 Apr 20

PMID : 26773055






1 Functional Relationships(s)
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1 Here we show that accumulation of unrepaired SSBs triggers a p53/Sp1-dependent downregulation of APE1, the endonuclease responsible for the DNA incision during BER. ssbs tumor protein p53 Homo sapiens