Pub. Date : 2015
PMID : 26770424
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of simvastatin on the expression of nephrin, podocin, and vascular endothelial growth factor (VEGF) in podocytes of diabetic rat. | Simvastatin | NPHS2 stomatin family member, podocin | Rattus norvegicus |
| 2 | Simvastatin (SVT) could reduce serum creatinine levels and the UAER, maintain the expression of nephrin and podocin, reduce the expression of VEGF, and improve the pathological changes of podocytes, which were much more pronounced at 8 weeks (P < 0.01). | Simvastatin | NPHS2 stomatin family member, podocin | Rattus norvegicus |
| 3 | Simvastatin could maintain the distribution of nephrin and podocin in podocytes, inhibit VEGF expression, and thus improve podocyte injuries and protect kidney functions in diabetic rats. | Simvastatin | NPHS2 stomatin family member, podocin | Rattus norvegicus |