Title : The angiotensin II receptor antagonist, losartan, enhances regulator of G protein signaling 2 mRNA expression in vascular smooth muscle cells of Wistar rats.

Pub. Date : 2016 May

PMID : 26763849






2 Functional Relationships(s)
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1 RGS2 mRNA expression significantly increased with Ang II stimulation, and this increase was almost completely abolished by olmesartan, a potent AT1R-specific blocker. olmesartan angiotensinogen Rattus norvegicus
2 Moreover, pretreatment with olmesartan abolished Ang II-mediated RGS2 mRNA expression. olmesartan angiotensinogen Rattus norvegicus