Title : Adaptation to AI Therapy in Breast Cancer Can Induce Dynamic Alterations in ER Activity Resulting in Estrogen-Independent Metastatic Tumors.

Pub. Date : 2016 Jun 1

PMID : 26763249






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 EXPERIMENTAL DESIGN: Global ER chromatin immuno-precipitation (ChIP)-seq analysis of AI-resistant cells identified steroid-independent ER target genes. Steroids estrogen receptor 1 Homo sapiens
2 EXPERIMENTAL DESIGN: Global ER chromatin immuno-precipitation (ChIP)-seq analysis of AI-resistant cells identified steroid-independent ER target genes. Steroids estrogen receptor 1 Homo sapiens
3 Genome-wide ER-DNA-binding analysis in AI-resistant cell lines identified a subset of classic ligand-dependent ER target genes that develop steroid independence. Steroids estrogen receptor 1 Homo sapiens
4 Genome-wide ER-DNA-binding analysis in AI-resistant cell lines identified a subset of classic ligand-dependent ER target genes that develop steroid independence. Steroids estrogen receptor 1 Homo sapiens