Title : Intranasal curcumin ameliorates airway inflammation and obstruction by regulating MAPKinase activation (p38, Erk and JNK) and prostaglandin D2 release in murine model of asthma.

Pub. Date : 2016 Feb

PMID : 26761722






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These investigations suggest that intranasal curcumin (2.5 and 5.0 mg/kg) regulates airway inflammation and airway obstruction mainly by modulating cytokine levels (IL-4, 5, IFN-y and TNF-alpha) and sPLA2 activity thereby inhibiting PGD2 release and COX-2 expression. Curcumin interleukin 4 Mus musculus